RNase P branches out from RNP to protein: organelle-triggered diversification?

نویسندگان

  • Katherine C Goldfarb
  • Sumit Borah
  • Thomas R Cech
چکیده

RNase P is the enzyme that removes 5' leader sequences from precursor tRNAs. Remarkably, in most organisms, RNase P is a ribonucleoprotein particle where the RNA component is responsible for catalysis. In this issue of Genes & Development, Gutmann and colleagues (pp. 1022-1027) report the first organism, Arabidopsis thaliana, to employ protein-only RNase P in both its nucleus and organelles. An intriguing possibility is that replacement of RNase P ribonucleoprotein particles (RNPs) by proteins may have been triggered by the acquisition of organelles.

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عنوان ژورنال:
  • Genes & development

دوره 26 10  شماره 

صفحات  -

تاریخ انتشار 2012